BRCCH Early-Career Programme 2022

Join the BRCCH's Early-Career Events 2022

The BRCCH endeavours to foster the development of aspiring young researchers who will pioneer the next frontiers in global paediatric medicine and health. The BRCCH’s Early Career Programme aims to provide unique opportunities for its community members to gain know-how in research areas at the heart of the Centre’s mission and to grow their global network.

This year, the BRCCH invites its early-career community members to join local and international speakers in a series of interactive workshops on topics across the Centre’s mandate.

Events Schedule

Understanding Key Needs in Global Paediatric Health

Tuesday, May 24th 2022 (main lecture 14.00-15.45; roundtable 16.00-17.15 pm CET)

Basel Biozentrum, room U1.191

Main Speaker: Prof Yvonne Maldonado, Stanford University, USA

Moderator: Prof Julia Dratva, Zurich University of Applied Sciences (ZHAW) & University of Basel, Switzerland

Panel members: Prof Alan Stein, University of Oxford, UK; Dr Marc Birkhölzer, University of Basel, Switzerland; Prof Thomas Berger, Secretary and Chief Medical Advisor at NEO FOR NAMIBIA

Participants will learn about the particularities and challenges of conducting translational research in paediatric health. Participants will also gain perspective on the biggest medical gaps in paediatric health today across high-, middle- and low-income countries. The lecture will be followed by an interactive debate with a panel of experts on the topic: How the COVID-19 Pandemic has affected Global Paediatric Health. The discussion will mainly focus on: i) mental health in young people, ii) disruption to life-saving paediatric health services such as immunisation and antenatal care.

Find out more about our speakers below

For more information and registration, contact Dr. Amandine Bovay, BRCCH Scientific Officer and Development Manager (amandine.bovay@brc.ch)

Programme Speakers:

Prof Yvonne Maldonado
Division of Infectious Diseases, Department of Pediatrics
Department of Epidemiology and Population Health                                 Stanford University School of Medicine, USA

Yvonne Maldonado is Professor of paediatrics, epidemiology, and population health, and Chief of the division of paediatric infectious diseases at the School of Medicine, Stanford University. She also currently serves as Stanford Medicine’s Senior Associate Dean of Faculty Development and Diversity. Prof Maldonado's research focuses on the epidemiology and prevention of viral infectious diseases such as paediatric HIV, polio, measles and Ebola. Her work on mother-to-child transmission of HIV in sub-Saharan Africa is credited for preventing hundreds of thousands of newborns from acquiring HIV. She also leads research on the development and implementation of vaccines in low- and middle-income countries.

Visual: Stanford University

Prof Julia Dratva
Institute of Public Health, ZHAW Zurich University of Applied Sciences, Switzerland
Medical Faculty, University of Basel, Switzerland

Prof Julia Dratva is a public health expert with a focus on child and adolescent health and early life factors of health and disease. She is the Head of the Public Health Research Unit at the Zurich University of Applied Sciences (ZHAW) and an Assistant Professor in the Medical Faculty at the University of Basel.

Prof Dratva is a medical doctor by training with a background in internal medicine. She also holds a Master degree in Public Health and a Specialist Certification (FMH) for "Prevention and Public Health". She has a particular interest in the life course approach to health and disease in research and teaching, addressing vulnerable groups and vulnerable time spans. She also has research interests in cardiovascular health, health monitoring, health literacy and digital health.

Prof Alan Stein
Department of Psychiatry, University of Oxford, UK

Alan Stein is Professor of Child & Adolescent Psychiatry at the University of Oxford, Honorary Professor in the School of Public health at the University of Witwatersrand and a member of the faculty of the African Health Research Institute, South Africa. His main area of research concerns the development of children and adolescents in the face of adversity. Ultimately the priority is to develop interventions. He has led three Lancet series on: i) The mental health of internally displaced and refugee children, ii) Perinatal mental health, iii) The communication of life-threatening conditions to children.

Prof Thomas Berger
Secretary and Chief Medical Advisor at NEO FOR NAMIBIA - Helping Babies Survive

Prof Thomas Berger is a paediatrician specialised in neonatology and intensive care. With more than 25 years of experience in neonatology in various high-income countries, he decided to share his knowledge with physicians and nurses in less privileged countries. Therefore, he and his wife founded the non-profit organisation NEO FOR NAMIBIA – Helping Babies Survive in 2017. The team has just launched their 14th mission in Rundu State Hospital to improve neonatal and paediatric care in Namibia.

Dr Marc Birkhölzer
Psychiatrist, University of Basel, Swizterland

Dr Marc Birkhölzer is currently a senior physician at the Juvenile Forensic Department of the Psychiatric University Clinics of Basel (UPK). His research focuses on personality disorders. Over the years, he has built an extraordinary network of collaborators in countries all over the world.

Webinar: Community-based COVID-19 Testing in Lesotho and Zambia

Webinar: Community-based COVID-19 Testing in Lesotho and Zambia

Visual: SolidarMed & Swiss TPH

 

Description:  The BRCCH cordially invites you to join us online for a webinar looking at Community-based COVID-19 testing in Lesotho and Zambia. This event will highlight research progress of the collaborative project between Dr Kwame Shanaube (Zambart) and Dr Klaus Reither (Swiss TPH) on the effects of community-led interventions in mitigating the COVID-19 epidemics in Lesotho and Zambia. The BRCCH and the European & Developing Countries Clinical Trials Partnership (EDCTP) partnered on a joint initiative to support multi-national collaborations for research to mitigate COVID-19, particularly in low- and middle-income countries.

When: Wednesday, April 27th, 2022 from 15:30-17:00 CET

Where: Online, Zoom seminar

Registration: HERE

Schedule:

      • Welcome by BRCCH Director Prof Georg Holländer
      • Keynote lecture by Dr Kwame Shanaube (Zambart), Dr Klaus Reither (Swiss TPH) & their research teams:
              1. Overview of the joint BRCCH-EDCTP project: Improving Access to SARS-CoV-2 Screening and Testing through Community-based COVID-19 Case-Finding and the Use of Digital Solutions in Lesotho and Zambia
              2. Comparing different approaches of community-based SARS-CoV-2 testing in Lesotho and Zambia
              3. Barriers and facilitators to SARS-CoV-2 testing at community-based testing sites
              4. Evaluation of SARS-CoV-2 tests and testing approaches
      • Plenary discussion
      • Closing

Keynote Speakers:

 

 

Dr Kwame Shanaube

Zambart & School of Public Health, University of Zambia

Dr Kwame Shanaube is Deputy Director of Research (Quantitative) at Zambart, a multidisciplinary research organisation that conducts a range of studies including clinical trials, epidemiological studies and laboratory-based diagnostic studies. She is a clinician with a Master’s degree in public health and a PhD in TB clinical epidemiology. She is also an honorary lecturer at the University of Zambia School of Public Health. Her research interests cover a wide range of disciplines, including TB/HIV epidemiology, community-based cluster randomised trials, operational research through evaluation of field diagnostics and adolescent health. She is also the country’s Principal Investigator for a large international TB consortium (the TREATS Project) and the overall Principal Investigator for the TREATS-COVID study, both funded by the EDCTP.

 

Dr Klaus Reither

Clinical Research Unit, Swiss Tropical and Public Health Institute

Dr Klaus Reither is Head of the Clinical Research Unit and the leader of the Clinical TB Research Group at the Swiss Tropical and Public Health Institute (Swiss TPH). He oversees and coordinates clinical research projects conducted by Swiss TPH and his research responsibilities comprise the set-up, implementation, coordination and supervision of clinical research projects, with an emphasis on TB clinical trials at Swiss TPH’s international partner organisations such as the Ifakara Health Institute in Tanzania, the National Centre of Tuberculosis and Lung Diseases in Georgia and SolidarMed in Lesotho.

Dr Reither is Lead Investigator of the BRCCH COVID-19 project: MistraL - Mitigation Strategies for Communities with COVID-19 Transmission in Lesotho Using Artificial Intelligence on Chest X-rays and Novel Rapid Diagnostic Tests. Together with Dr Kwame Shanaube, he also co-leads a BRCCH-EDCTP collaborative project on Improving Access to SARS-CoV-2 Screening and Testing through Community-based COVID-19 Case-Finding and the Use of Digital Solutions in Lesotho and Zambia.

 

Impact of COVID-19 on Global Paediatric Health – Interactive debate

Impact of COVID-19 on Global Paediatric Health

Join us during an interactive debate with a panel of experts on the topic: How the COVID-19 Pandemic has affected Global Paediatric Health. The discussion will mainly focus on: i) mental health in young people, ii) disruption to life-saving paediatric health services such as immunisation and antenatal care.

Tuesday, May 24th 2022 (16.00-17.15 pm CET)

Moderator: Prof Julia Dratva, Zurich University of Applied Sciences (ZHAW) & University of Basel, Switzerland

Panel members: Prof Yvonne Maldonado, Stanford University, USA; Prof Alan Steiner, University of Oxford, UK; Dr Marc Birkhölzer, University of Basel, Switzerland; Prof Thomas Berger, Secretary and Chief Medical Advisor at NEO FOR NAMIBIA

Find out more about our speakers below

The event is taking place in a hybrid format:

The number of seats at Basel Biozentrum is limited, please register here.

Interested in joining virtually? Sign up here!

For more information, contact Dr Amandine Bovay, BRCCH Scientific Officer and Development Manager (amandine.bovay@brc.ch)

Programme Speakers:

Prof Yvonne Maldonado
Division of Infectious Diseases, Department of Pediatrics
Department of Epidemiology and Population Health                                 Stanford University School of Medicine, USA

Yvonne Maldonado is Professor of paediatrics, epidemiology, and population health, and Chief of the division of paediatric infectious diseases at the School of Medicine, Stanford University. She also currently serves as Stanford Medicine’s Senior Associate Dean of Faculty Development and Diversity. Prof Maldonado's research focuses on the epidemiology and prevention of viral infectious diseases such as paediatric HIV, polio, measles and Ebola. Her work on mother-to-child transmission of HIV in sub-Saharan Africa is credited for preventing hundreds of thousands of newborns from acquiring HIV. She also leads research on the development and implementation of vaccines in low- and middle-income countries.

Visual: Stanford University

Prof Julia Dratva
Institute of Public Health, ZHAW Zurich University of Applied Sciences, Switzerland
Medical Faculty, University of Basel, Switzerland

Prof Julia Dratva is a public health expert with a focus on child and adolescent health and early life factors of health and disease. She is the Head of the Public Health Research Unit at the Zurich University of Applied Sciences (ZHAW) and an Assistant Professor in the Medical Faculty at the University of Basel.

Prof Dratva is a medical doctor by training with a background in internal medicine. She also holds a Master degree in Public Health and a Specialist Certification (FMH) for "Prevention and Public Health". She has a particular interest in the life course approach to health and disease in research and teaching, addressing vulnerable groups and vulnerable time spans. She also has research interests in cardiovascular health, health monitoring, health literacy and digital health.

Prof Alan Stein
Department of Psychiatry, University of Oxford, UK

Alan Stein is Professor of Child & Adolescent Psychiatry at the University of Oxford, Honorary Professor in the School of Public health at the University of Witwatersrand and a member of the faculty of the African Health Research Institute, South Africa. His main area of research concerns the development of children and adolescents in the face of adversity. Ultimately the priority is to develop interventions. He has led three Lancet series on: i) The mental health of internally displaced and refugee children, ii) Perinatal mental health, iii) The communication of life-threatening conditions to children.

Prof Thomas Berger
Secretary and Chief Medical Advisor at NEO FOR NAMIBIA - Helping Babies Survive

Prof Thomas Berger is a paediatrician specialised in neonatology and intensive care. With more than 25 years of experience in neonatology in various high-income countries, he decided to share his knowledge with physicians and nurses in less privileged countries. Therefore, he and his wife founded the non-profit organisation NEO FOR NAMIBIA – Helping Babies Survive in 2017. The team has just launched their 14th mission in Rundu State Hospital to improve neonatal and paediatric care in Namibia.

Dr Marc Birkhölzer
Psychiatrist, University of Basel, Swizterland

Dr Marc Birkhölzer is currently a senior physician at the Juvenile Forensic Department of the Psychiatric University Clinics of Basel (UPK). His research focuses on personality disorders. Over the years, he has built an extraordinary network of collaborators in countries all over the world.

Webinar: Future of COVID-19 Research

Webinar: Future of COVID-19 Research

**Update October 28th, 2021 ** Thank you to everyone that attended our webinar! We had a great turnout-- in case you missed the presentations or you would like to watch them again, you can now stream them below or on our YouTube channel.

visual: background image courtesy of National Institute of Allergy and Infectious Diseases

 

Description: The BRCCH cordially invites you to join us online for a webinar looking at The Future of COVID-19 Research. This event will highlight significant research progress and the roadmap ahead related to immunology, epidemiology and bioengineering. Gain insights from our keynote speakers and engage with them during the Q&A panel discussion.

When: Thursday, October 21st, 2021 from 15:00-17:00 CET

Where: online, livestream Zoom seminar

Schedule:
Welcome by BRCCH Vice Director Prof Sai Reddy
Keynote lecture by Prof Teresa Lambe OBE (University of Oxford)
     "Development and testing of the Oxford/AstraZeneca vaccine"
Keynote lecture by Prof Benjamin Murrell (Karolinska Institutet)
     "Neutralizing SARS-CoV-2 variants"
Keynote lecture by Prof Sai Reddy (ETH Zurich and BRCCH)
     "Identifying prospective variants of SARS-CoV-2 by deep mutational learning"
Q&A Panel Discussion
Closing

Webinar Archive

Prof Teresa Lambe OBE (University of Oxford) presents "Development and Testing of the ChAdOx1 nCoV-19/AZD1222 Vaccine" originally webcast on October 21st, 2021.

 

Prof Benjamin Murrell (Karolinska Institutet) presents "Neutralizing SARS-CoV-2 Variants" originally webcast on October 21st, 2021.

 

Prof Sai Reddy (ETH Zurich and BRCCH) presents "Identifying Prospective Variants of SARS-CoV-2 by Deep Mutational Learning" originally webcast on October 21st, 2021.

Keynote Speakers:

Prof Teresa Lambe OBE
The Lambe Group for Emerging Pathogens
The Oxford Vaccine Group and the Jenner Institute Laboratories
Dept of Paediatrics, University of Oxford

Assoc Prof Lambe will share her research insights into the immune response to SARS-CoV-2 and its vaccine. Her research group is part of the Covid-19 vaccine trial in the UK and has co-designed the vaccine and led the development and testing of the immune response after vaccination.

Prof Lambe’s research investigates the establishment of protective immune responses following vaccination and the formation of adaptive immune memory. She is particularly interested in delineating the immune response post vaccination and also post natural infection to help develop vaccines and define correlates of protection. At the University of Oxford, her group uses platform technologies to develop vaccines against emerging and re-emerging pathogens. The group is currently developing vaccines against a number of outbreak pathogens including Crimean-Congo haemorrhagic fever virus, Lassa virus, Nipah virus, Influenza, Ebolavirus and coronaviruses.

Visual: John Cairns/University of Oxford

Prof Benjamin Murrell
Department of Microbiology, Tumor and Cell Biology
Karolinska Institutet

Prof Murrell will speak about his work on the H2020 CoroNAb project, studying antibodies and isolating nanobodies against SARS-CoV-2.

Prof Murrell's previous research interests surrounded the evolution of the HIV envelope protein, and antibodies against it. Recently, he has applied this expertise to SARS-CoV-2 and its variants. Together with colleagues, he has identified nanobodies from immunized alpacas that may be potential SARS-CoV-2 therapeutics, and has conducted preclinical immunization studies attempting to boost responses to SARS-CoV-2 variants. This work is part of the CoroNAb consortium research project, funded under Horizon2020 as part of the EU’s emergency funding call for COVID-19.

Visual: Karolinska Institutet

Prof Sai Reddy
Laboratory for Systems and Synthetic Immunology
Department of Biosystems Science and Engineering, ETH Zurich
And Vice Director BRCCH

Prof Reddy shares his recent work on developing a simultaneous diagnostic and genomic surveillance method for SARS-CoV-2 based on targeted deep sequencing. He will also present new data from his group related to identifying variants of SARS-CoV-2 using a novel method called deep mutational learning. 

Prof Reddy’s research is focused on the emerging field of systems and synthetic immunology, with an aim towards developing technologies relevant to immunotherapy and biotechnology. He has developed a number of methods in systems immunology to improve our understanding of adaptive immunity, with a particular focus on immune repertoire sequencing. Recently, he founded two spin-off companies, deepCDR Biologics and Engimmune Therapeutics, which are both based on technologies developed in his research group on engineering antibodies or T cells.

Webinar: Insights Into COVID-19 Research

Webinar: Insights Into
COVID-19 Research

The BRCCH invites you to join us online for free webinars on COVID-19.

**Update September 17th, 2020 ** Thank you to everyone that attended our webinars in September! We had a great turnout-- in case you missed the presentations or you would like to watch them again, you can now stream them below or on our YouTube channel

    Description: The pandemic is placing the world in a stress test that is unprecedented. In response, organizations across sectors from research to nonprofit are mobilizing resources and taking action. This 3-part webinar series will highlight the BRCCH's ongoing collaborative research efforts in Switzerland, as well as dip into the global conversation about the current challenges and latest developments in the race to respond to the pandemic, with a focus on low- and middle-income countries.

    Sept 2nd & 9th: We will take an in-depth look into recently launched research projects focused on diagnostics and the immunology of COVID-19, as well as others focused on novel medical interventions for COVID-19. The projects are part of our recent Fast Track Initiative for COVID-19.

    Sept 16th: During the panel discussion, we will hear first hand from international experts about the current landscape of public health and how technology and partnerships spanning borders could meet current challenges in the pandemic.

    Register: closed. In case you missed the webinars, you can now watch them here (scroll down) or on our Youtube channel
    More: Download our programme below for info on the talks and speakers

    Banner image: Produced by the National Institute of Allergy and Infectious Diseases (NIAID), this highly magnified, digitally colorized transmission electron microscopic (TEM) image reveals ultrastructural details exhibited by three, spherical shaped, Middle East respiratory syndrome coronavirus (MERS-CoV) virions.

    Webinar Archive

    Prof Janos Vörös (ETH Zurich) & PD Dr Michael Osthoff (University Hospital Basel) present "A mobile, rapid diagnostic test system for COVID-19 based on lateral flow assays diagnosing SARS-CoV-2 infections at point-of-need," originally webcast on Sep 2nd, 2020.

     

    Prof Andreas Moor (ETH Zurich) presents "B cell immunity in convalescent COVID-19 patients with the aim of identifying high-affinity antibodies against SARS-CoV-2" originally webcast on Sep 2nd, 2020.

     

    Prof Melissa Penny (Swiss TPH) & Prof Roland Regoes (ETH Zurich) present "Modelling and machine learning to optimise medical interventions and health strategies for emergency response to the pandemic" originally webcast on Sep 9th, 2020.

     

    Prof Thomas Erb (University Children's Hospital Basel) & Prof Mirko Meboldt (ETH Zurich) present "The challenge of ventilation in the COVID-19 pandemic - improved patient care with low-cost ventilators based on novel integrated pressure sensors" originally webcast on Sep 9th, 2020.

     

    International Panel Discussion
    Prof Alain Labrique (Global mHealth Initiative, Johns Hopkins University) &
    Dr Solomzi Makohliso (EssentialTech, EPFL) &
    Prof Marcel Tanner (Swiss Academy of Sciences | Fondation Botnar)  &
    Akhona Tshangela (Africa Centres for Disease Control and Prevention) &
    Moderated by Dr Maxine Mackintosh (One HealthTech | The Alan Turing Institute)

    Inaugural BRCCH Spotlight Day

    The inaugural Spotlight Day of the BRCCH marked the start of our initiative to build a community, both locally and globally, around the central mission of improving the health and well-being of children and adolescents worldwide. This event was an opportunity for local and international community to meet, start new dialogues and enable fruitful collaborations.

    More than 200 visitors joined the BRCCH at the inaugural Spotlight Day on January 30, 2020 – a great turnout to the Centre's first public event. After inspiring welcome addresses by Andrea Schenker-Wicki and Detlef Günther, four new BRCCH Multi-Investigator Projects showcased their vision for the next 5 years. Three international keynote speakers gave new perspectives on how research can be applied and translated. With this event, the BRCCH welcomed our new research projects at the Centre and the start of their research activities at the BRCCH.

    Watch a summary of the event:

     

    Artist Alex Hughes (Drawnalism) illustrated the event:

       

      The event programme: