BRCCH Seminar 18 Nov - Importance of the Microbiome in Paediatric Health

Visual: Ronja Rappold


Description:  The BRCCH cordially invites you to join our seminar addressing the importance of the microbiome in paediatric health. Prof Emma Slack (ETH Zurich, Switzerland) will share her work on the development of novel intervention strategies for inborn errors of metabolism and neonatal sepsis using advancements in microbiota bioengineering. Prof Mathias Hornef (University Hospital Aachen, Germany) will highlight his research on the postnatal microbiotic colonisation in the intestines and the development of the mucosal adaptive immune system after birth.

When: Friday, November 18th, 2022 from 16:00-17:15 CET, to be followed by an apéro

Where: Hybrid Zoom / Room HIL E7 – Hörsaal, ETH Zurich Hönggerberg Campus, Stefano-​​Franscini-​Platz 5, 8093 Zurich

Zoom Registration: HERE

In-person Registration: HERE
Directions and location information


      • Welcome by Prof Sai Reddy (Vice Director, BRCCH)
      • Prof Emma Slack (ETH Zurich): "Precision Microbiota Engineering for Child Health"
      • Prof Mathias Hornef (University Hospital Aachen, Germany): "Ontogeny of the Host-Microbial Interaction in the Intestine"
      • Q&A and Closing
      • Networking Apéro

Keynote speakers:

Prof Emma Slack

ETH Zurich, Switzerland

Prof Slack is a professor at the Department of Health Sciences and Technology (D-HEST) at ETH Zurich. The Slack group’s research focuses on understanding and manipulating the interactions between microbes and host on microbial surfaces, particularly in the intestine. Their work involves developing novel mucosal vaccines for application in human and veterinary medicine, as well as establishing unique tools for the functional analysis of the microbiota in animal models. In combination, this will allow the group to rationally and robustly manipulate host-microbiota and host-pathogen interactions for the promotion of health.

Prof Slack also leading a BRCCH-funded project to develop novel tools to precisely engineer the microbiota of individuals with inborn errors of metabolism or neonatal sepsis (find out more here).


Prof Mathias Hornef

University Hospital Aachen, Germany

Prof Hornef studied medicine and after a postdoctoral period at the Karolinska Institute in Stockholm (Sweden) and clinical positions at the Albert Ludwigs University of Freiburg and Hannover Medical School (Germany), he became a full professor and head of the Institute of Medical Microbiology at the RWTH Aachen University (Germany). In recent years, he and his group have worked on the establishment of neonatal gastrointestinal infection models with bacterial, viral and parasitic pathogens as well as the postnatal establishment of the enteric microbiota and the maturation of the mucosal adaptive immune system after birth.