Prof Sai Reddy is Vice Director of the BRCCH and an expert in systems and synthetic immunology. He holds a professorship at ETH Zurich and is the co-founder of the biotechnology spin-off company deepCDR Biologics. Together with Director Georg Holländer, Prof Reddy is the Centre’s academic leader and is responsible for its strategic orientation and initiatives.

Prof Reddy is an associate professor at ETH Zurich in the Department of Biosystems Science and Engineering (D-BSSE). His research is focused on the emerging field of systems and synthetic immunology, with an aim towards developing technologies relevant to immunotherapy and biotechnology. Systems immunology uses quantitative multiscale measurements and computational biology in order to describe and understand the complexity of the immune system. Prof Reddy has developed a number of methods in systems immunology to improve our understanding of adaptive immunity, with a particular focus on immune repertoire sequencing. Synthetic immunology uses methods in molecular and cellular engineering to control immune cell function and behaviour. Prof Reddy’s group has established methods of reprogramming immune cells for applications in protein engineering and cellular immunotherapy, with an emphasis on immunogenomic engineering. In addition to the academic community, Prof Reddy has done work to support the biotechnology industry, including several sponsored research projects with local and international companies, such as Roche (CH), Novartis (CH) and UCB-Celltech (UK). Recently, he founded a company (deepCDR Biologics) based on technologies developed in his research group on antibody drug discovery and engineering.