After completing his master studies in molecular and cellular biology at the University of Heidelberg, Germany, Jan Michler joined the research group of Prof Andreas Moor in Basel in October 2020. Using a combination of single-cell RNA sequencing, immune cell receptor sequencing and antigen-binding specificities analysis, the group studies immune responses in high depth and resolution. In his PhD project, Jan investigates aspects of the development of human immune memory in the context of SARS-CoV-2 infections and vaccinations. This work yields fascinating insights into our body’s defence against pathogens.